Methylene Blue

Methylene Blue acts by inhibiting nitric oxide synthase and guanylate cyclase, influencing cellular respiration and energy production. This synthetic compound, originally derived from aniline, is a blue dye that has been utilized in various scientific settings since its discovery in the late 19th century. Initially, researchers were drawn to its potential in treating malaria and methemoglobinemia, sparking broader interest in its metabolic effects. It is also being studied for its neuroprotective properties. Today, it is primarily studied for its effects on:

• Neurodegenerative diseases
• Cognitive enhancement
• Mitochondrial function
• Metabolic disorders

Further studies are exploring its impact on oxidative stress.

PeptideSource editorial · Updated Jul 19, 2026