Pentapeptide-18
cosmeticPentapeptide-18 is a research-use-only peptide. PeptideSource compares suppliers on purity, COAs, and price-per-mg.
Also known as: Leuphasyl
Pentapeptide-18, also known as Leuphasyl, is a synthetic peptide used in cosmetic applications. It works by modulating the release of neurotransmitters at neuromuscular junctions, leading to reduced muscle contractions. Early work on Pentapeptide-18 focused on its potential to mimic the effects of enkephalins, a family of endogenous opioid peptides. This peptide's ability to interact with the skin's muscle fibers has made it a popular subject in wrinkle reduction studies. Today, it is primarily studied for its effects on:
- Wrinkle reduction
- Skin smoothing
- Muscle relaxation
PeptideSource editorial · Updated Jul 18, 2026
For research use only. PeptideSource does not sell peptides directly. Compare third-party supplier listings at your own discretion.
Compare suppliers
Size | ||
|---|---|---|
| Shop now | Shop | Shop |
| Product | Pentapeptide-18 Leuphasyl | Pentapeptide-18 Leuphasyl Topical |
| Size | 200 mg | 200 mg |
| Price | $215.00 | $230.00 |
| Price/mg | $1.08/mg | $1.15/mg |
| Price change | 0% (16d) | 0% (10d) |
| Stock | In stock | In stock |
| Shipping | Same-day dispatch | Same/next-day dispatch |
| Reviews | 4.9(15) | 1.0(4) |
| Purity | 99% | 99% |
| COA | — | — |
| Bulk discount | — | — |
