SYN-AKE

SYN-AKE, or Dipeptide Diaminobutyroyl Benzylamide Diacetate, is a synthetic peptide that functions by mimicking the paralytic effect of a component found in the venom of the Temple Viper (Tropidolaemus wagleri). Interest in SYN-AKE started around the early 2000s when researchers explored its potential for reducing facial muscle contractions. Its unique ability to inhibit neuromuscular activity without the need for invasive procedures has distinguished it in the cosmetic industry. Beyond that, work continues on refining its application techniques. Today, it is primarily studied for its effects on:

• Reduction of facial wrinkles
• Muscle relaxation in cosmetic applications
• Non-invasive anti-aging treatments

SYN-AKE's mechanism of action draws inspiration from nature’s own way of managing muscle activity.

PeptideSource editorial · Updated Jul 18, 2026